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doi:10.1096/fj.09-142307 Malinda KM, Goldstein AL, Kleinman HK

With 2.5 mL of BAC water in an 80 mg vial, each injection is a 0.1 mL, or 10-unit, draw

Research Protocol Summary Study Protocol: 0.25 mg AOD-9604 administered intra-articularly via ultrasound guidance Frequency: Weekly injections Duration: 4-7 weeks in research studies Combination Therapy: 6 mg hyaluronic acid co-administered for enhanced effects Assessment Timeline: Significant improvements observed by 8-9 weeks Note: These protocols are from animal research and have not been validated for human use

Improved Mobility: Increases flexibility and joint mobility, particularly important for athletes and the elderly